About This Study

Key details about the heart failure research study

Study Purpose

Advancing Heart Failure Treatment

This clinical trial investigates new therapeutic approaches for adults living with heart failure and obesity, focusing on improving quality of life and cardiac function.

Locations

4 Convenient California Sites

Study visits are available at Tarzana, Huntington Park, San Diego, and Northridge. All locations offer free parking and complimentary transportation.

Study Status

Now Enrolling

We are actively enrolling qualified participants at all four locations. Our teams are reviewing applications and conducting screenings on an ongoing basis.

Who Can Join

Adults with Heart Failure & Obesity

Adults who have been diagnosed with heart failure and obesity may be eligible. Final eligibility is determined at your screening visit.

Understanding Heart Failure & Obesity

Heart failure is a chronic condition where the heart cannot pump blood effectively enough to meet the body's needs. It often develops gradually and can significantly impact daily activities and quality of life.

Obesity is a recognized risk factor for heart failure and can worsen symptoms by increasing strain on the heart. The combination of these conditions presents unique challenges and requires specialized medical management.

Clinical trials like this one are essential to finding new therapies that can improve heart function, reduce symptoms, and enhance overall well-being for people living with both conditions.

What is Heart Failure?

A chronic condition where the heart muscle doesn't pump blood as well as it should, causing symptoms like shortness of breath, fatigue, and fluid retention.

The Connection to Obesity

Obesity increases the workload on the heart and contributes to conditions that can lead to or worsen heart failure, including high blood pressure, diabetes, and sleep apnea.

Why Clinical Trials Matter

Research is advancing our understanding of how to better manage heart failure in patients with obesity, with new therapies showing promise in improving outcomes and quality of life.

Participant Benefits

Everything you receive as a study participant — at no cost to you

$

$50–$250 Per Visit

Receive compensation for your time and travel at each completed study visit, recognizing the value of your participation in advancing heart failure research.

🚗

Free Transportation

Complimentary transportation to and from any of our four research sites for all scheduled visits. Free parking is also available on-site.

💊

No-Cost Study Care

All study-related medication, lab work, exams, and medical care are provided completely free of charge throughout your participation.

❤️

Cardiac Health Monitoring

Regular heart function assessments, lab tests, and comprehensive medical monitoring by our dedicated cardiology research team.

👨‍⚕️

Expert Medical Team

Access to experienced cardiology research physicians and study coordinators who are focused on your safety and health outcomes.

🔬

Advance Heart Research

Help develop new treatments that could improve outcomes for millions of people living with heart failure and obesity worldwide.

Do You Qualify?

You may be eligible to participate if you meet the following general criteria. Final eligibility is confirmed at your screening visit.

• ✓ Adults 18 years of age or older
• ✓ Diagnosed with heart failure as confirmed by a healthcare provider
• ✓ Living with obesity (BMI typically ≥30 kg/m²)
• ✓ Able to attend study visits at one of our four California locations

Not sure if you qualify? Our study team is happy to answer your questions. Give us a call or sign up below — the process takes just a few minutes.

Sign Up to Learn More 📞 Call Us

Study Locations

Choose the location that's most convenient for you

📍 Tarzana

Valiance Clinical Research — Tarzana Facility

📞 818-938-9167

📍 Huntington Park

Valiance Clinical Research — Huntington Park Facility

📞 323-484-0508

📍 San Diego

Valiance Clinical Research — San Diego Facility

📞 858-352-6449

📍 Northridge

Valiance Clinical Research — Northridge Facility

📞 747-799-0050

What to Expect

A step-by-step look at the study journey from sign-up to completion

1

Sign Up & Phone Screening

Submit your information and our study coordinator will reach out within 1–2 business days.

• Brief phone call to review basic eligibility (5–10 minutes)
• Answer questions about your heart failure and obesity diagnosis
• Ask any questions you have about the study
• Choose your preferred study location

2

In-Person Screening Visit

If eligible by phone, you'll visit your chosen facility for a full medical evaluation.

• Meet the research team and tour the facility
• Review the informed consent document thoroughly
• Physical examination and medical history review
• Cardiac function tests, lab work, and vital signs
• Confirm final eligibility for enrollment

3

Enrollment & Consent

If you qualify and choose to enroll, you'll officially become a study participant.

• Sign informed consent after all your questions are answered
• Receive your full study schedule and participant materials
• Get 24/7 contact information for the study team

4

Study Participation & Visits

Attend regular scheduled visits for treatment and cardiac health monitoring.

• Receive study medication as part of the treatment protocol
• Regular heart function assessments and health monitoring
• Compensation issued at each completed visit
• Report any health changes or symptoms to the study team
• Free transportation available for every visit

5

Study Completion

Complete your final visit and receive a summary of your health data and recommended next steps.

• Final cardiac health assessment and evaluation
• Discussion of findings with the study physician
• Guidance on continued heart care going forward
• Receive your final visit compensation

Frequently Asked Questions

Answers to common questions about the study and heart failure

All Questions General About Heart Failure About This Study Eligibility Compensation Safety & Rights

What is a clinical trial?+

A clinical trial is a research study that evaluates the safety and effectiveness of new medical treatments. All clinical trials follow strict scientific and ethical standards and are overseen by independent review boards to protect participants. They are essential for developing better therapies for serious conditions like heart failure.

Why should I consider participating?+

Participating gives you access to potentially promising new treatments at no cost, along with close monitoring from a dedicated medical team. You'll receive compensation for your time, free transportation, and have the opportunity to contribute to research that may benefit others living with heart failure and obesity. Many participants report feeling well-supported throughout the study.

Is participating in a clinical trial safe?+

Yes. Participant safety is the top priority. This study is conducted under strict protocols approved by an Institutional Review Board (IRB) and follows FDA and Good Clinical Practice (GCP) guidelines. You'll be closely monitored throughout, have access to the study team 24/7, and can withdraw at any time for any reason without penalty.

What exactly is heart failure?+

Heart failure is a chronic condition where the heart doesn't pump blood as efficiently as it should. It doesn't mean the heart has stopped working entirely, but rather that it's not meeting the body's demands for blood and oxygen. This can lead to symptoms like shortness of breath, fatigue, and fluid buildup.

How does obesity affect heart failure?+

Obesity puts extra strain on the heart by increasing the amount of blood the heart needs to pump and the distance it must be pumped. It also contributes to conditions like high blood pressure, diabetes, and sleep apnea, which can worsen heart failure. Managing both conditions together is important for overall health.

Can heart failure be treated?+

While heart failure is a chronic condition that requires ongoing management, many treatments can help control symptoms, improve quality of life, and slow progression. These include medications, lifestyle changes, and in some cases, medical devices or procedures. Clinical trials like this one are exploring new therapies that may offer additional benefits.

What does participation in this study involve?+

Participation involves regular scheduled visits to one of our four facilities for study treatment, heart function monitoring, and health assessments. You'll receive study medication as part of the protocol. All study-related care is provided at no cost, and you'll receive compensation at each completed visit. The study team will walk you through the full schedule before you make any commitment.

Can I continue seeing my regular doctor during the study?+

Yes. We strongly encourage you to maintain your relationship with your cardiologist and primary care physician. With your permission, we will coordinate with your existing healthcare providers to ensure continuity of care. It's important that all your doctors are informed of any changes in your health or medications throughout the study.

Which location should I choose?+

Choose whichever location is most convenient for you. All four facilities (Tarzana, Huntington Park, San Diego, and Northridge) offer the same high-quality care and follow the same study protocol. Free transportation is available at all locations if you need it.

What if I'm not sure about my heart failure diagnosis?+

Our screening team will review your medical history and confirm your diagnosis during the screening process. If you've been told you have heart failure or have symptoms like shortness of breath, fatigue, and swelling, we encourage you to apply. Having your medical records available will be helpful.

Do I need to be on heart failure medication to participate?+

Not necessarily. During the screening process, our medical team will review all your current medications and health status to determine if the study is appropriate for you. Being on or not being on medication does not automatically qualify or disqualify you.

What if I have other health conditions?+

Having other health conditions does not automatically disqualify you. Many people with multiple conditions successfully participate in clinical trials. Our medical team will conduct a full review of your health history during the screening visit to determine if the study is appropriate for you.

How much will I be compensated?+

Participants receive between $50 and $250 per completed study visit. The compensation amount varies based on the type and length of the visit. Visits involving more procedures or longer appointments are compensated at higher rates. You will receive a complete compensation schedule prior to enrollment.

How does the free transportation work?+

We provide complimentary transportation to and from all four facilities for all scheduled study visits. When scheduling each appointment, simply let our team know you need transportation and we will coordinate the details. Free on-site parking is also available if you prefer to drive yourself.

What if I need to reschedule a visit?+

We understand that unexpected situations arise. If you need to reschedule, please contact our study coordinator as early as possible. Occasional rescheduling is generally accommodated. Consistent attendance is important for your safety and the quality of the research, and compensation is provided for completed visits only.

Can I leave the study if I change my mind?+

Yes. Participation is entirely voluntary. You have the right to withdraw at any time, for any reason, without penalty or loss of any benefits you are otherwise entitled to. Simply notify the study team if you wish to discontinue. We may request an optional final safety visit to ensure your health is stable.

Will my personal and medical information stay confidential?+

Yes. Your information is fully protected under HIPAA regulations. Your personal identity will never appear in any study publications or reports. All research data is de-identified, meaning it cannot be traced back to you as an individual. Only authorized study staff have access to your identifiable records, and all data is stored securely.

Who oversees this study to protect participants?+

This study is reviewed and continuously monitored by an Institutional Review Board (IRB), an independent committee whose role is to protect participant rights and well-being. The study also follows FDA regulations and Good Clinical Practice (GCP) guidelines to ensure the highest standards of participant safety and research integrity.

What is the Informed Consent process?+

Before enrolling, you will be given a detailed Informed Consent document that explains the study's purpose, all procedures involved, potential risks and benefits, and your rights as a participant. You will have as much time as you need to review it, discuss it with family or your own doctor, and ask any questions. Signing means you agree to participate — but you may still withdraw at any point after signing.

Ready to See If You Qualify?

Sign up today or call the location nearest you. Our team will review your information and reach out within 1–2 business days.

Sign Up Now

Tarzana

818-938-9167

Huntington Park

323-484-0508

San Diego

858-352-6449

Northridge

747-799-0050

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