STUDY D7266C00001 · HCP REFERRAL AID

30-Second Heart Failure Prescreen

Use Yes, Unsure, or No. This tool identifies possible referrals; it does not determine study eligibility.

Patient contact

Limited referral information
1. Basic must haves
Any Yes needs site review
Patient is 18 years or older
Symptomatic heart failure, NYHA class II–IV
Most recent LVEF is greater than 40% with structural heart disease Left ventricular hypertrophy or left atrial enlargement on qualifying imaging.
NT-proBNP meets the likely study threshold At least 300 pg/mL without ongoing AF/flutter or 900 pg/mL with ongoing AF/flutter.
Currently receiving an oral loop or thiazide diuretic
Qualifying body size BMI ≥30, or BMI 25 to <30 with waist-to-height ratio ≥0.5.
2. Quick stop-sign check
ANY YES NEEDS SITE REVIEW
Recent acute cardiovascular event or major procedure At lACS, stroke, or TIA within 3 months; or specified major cardiac procedure within 90 days.
Major diabetes, kidney, liver, or pulmonary concern Type 1/secondary diabetes, HbA1c ≥10%, dialysis/eGFR <20, significant liver disease, or severe pulmonary disease.
Other major potential exclusion Pancreatitis; MTC/MEN2 history; recent GLP-1 therapy; pregnancy/breastfeeding; certain cardiomyopathies; or active malignancy not covered by protocol exceptions.