Driving Innovation in Healthcare

We oversee all phases of clinical research, from design to close-out, with a therapeutic focus and patient-centered approach, driving the advancement of better health for all.

Your Research, Accelerated

An evidence-based approach

Providing a blend of expertise, scalability, agility, and proactive engagement across all phases of clinical development.

Our Mission

Our mission is to advance medical knowledge and treatment with a patient-centered approach by offering innovative, personalized therapeutic options that enhance lives and positively impact patient outcomes, driving meaningful change in healthcare.

Our Values

We are committed to core values of innovation, inclusivity, integrity, compassion, respect, trust, collaboration, safety, quality, and patient empowerment, ensuring excellence in healthcare and fostering a supportive environment for all stakeholders.

Our Team

Our leadership team consists of diverse, experienced professionals from various disciplines, united by a shared passion for delivering exceptional patient care and driving excellence in healthcare services through collaboration and innovation.

Research-driven, People-Focused Healthcare

Valiance Clinical Research is a leader in advancing research aimed at preventing and treating diseases that impact people’s health through clinical trials. We strive to provide educational, informative, and transparent content for all. To those who have joined a clinical trial with us or are considering enrollment, we extend our heartfelt thanks and appreciation. Your partnership is essential as we work to develop groundbreaking new medicines and therapies.

Help Advance Medical Science

Human clinical trials are an essential component of medical research, playing a pivotal role in evaluating the safety and efficacy of new treatments. Our extensive network of healthy participants contributes to these studies for a variety of personal and scientific reasons. Regardless of your motivation for considering participation, it is important to ensure that a clinical trial aligns with your individual needs and circumstances. Participation is entirely voluntary, and you retain the right to decline enrollment or withdraw from a study at any time, should you choose to do so.

What is a Clinical Trial

Clinical trials are research studies involving volunteers that help scientists explore and create new methods to prevent, diagnose, or treat diseases and their symptoms. These studies may test investigational treatments such as new medications, combinations of drugs, innovative delivery methods for existing drugs, or medical devices. Before approval, new treatments undergo extensive testing, beginning in the laboratory, progressing to animal studies, and finally being evaluated in humans. To gain approval, a new medication or device must prove its safety and effectiveness, and in many cases, show greater benefits compared to existing products on the market.
What do the different phases of a clinical trial mean?

Clinical trials for investigational products, such as medications, devices, or procedures, are conducted in distinct phases to gather specific information about their safety, effectiveness, and potential applications. Phase 1 Studies Phase 1 trials involve a small group of participants (20-80), often healthy volunteers or patients with advanced diseases like cancer or mental health disorders. This is typically the first stage of human testing for a product. The primary objectives of Phase 1 are to: Assess safety Identify potential side effects Determine safe dosage ranges Understand how the body processes the product (pharmacokinetics and dynamics) These studies usually take several months, and about 70% of Phase 1 trials advance to Phase 2. Phase 2 Studies Phase 2 trials enroll a larger group (100-300 participants) with the specific condition being studied. These trials further evaluate safety and test whether the product achieves its intended effect in humans. Often randomized controlled trials May compare the investigational product with a placebo or standard treatment Frequently “blinded,” so neither participants nor researchers know who receives the active product Phase 2 studies typically last up to two years, with approximately 33% progressing to Phase 3. Phase 3 Studies Phase 3 trials involve thousands of participants with the disease or condition. These studies aim to: Confirm or further evaluate effectiveness Monitor side effects on a larger scale Compare the product with existing treatments Gather data needed for regulatory approval and marketing These randomized and blinded trials can take one to four years to complete. Around 25-30% of Phase 3 trials are successfully completed and submitted to the FDA for review and potential approval. Phase 4 Studies Also known as Post-Marketing Surveillance Trials, Phase 4 studies are conducted after FDA approval. They focus on: Collecting long-term data on risks and benefits Assessing the product's performance across diverse populations Monitoring for rare or delayed side effects Findings from Phase 4 studies can lead to changes in usage guidelines or even market withdrawal if significant safety concerns arise. Each phase of clinical trials plays a critical role in ensuring that investigational products are safe, effective, and ready for public use.
Why should I participate in a clinical trial?

Participating in a clinical trial offers the chance to explore a new treatment, which may or may not prove more effective than existing options. As a participant, you contribute to a deeper understanding of how treatments work across diverse populations, as responses can vary by race, gender, and other factors. Regulatory agencies like the FDA emphasize the importance of including people of different ages, races, ethnicities, and genders in clinical trials to ensure broad representation. Why Consider Joining a Clinical Trial? Early access to new treatments not yet available to the public Free access to study-related medications Potential compensation for participation in some studies Personal fulfillment from advancing medical research Voluntary participation—you can withdraw at any time Each clinical trial has specific eligibility requirements that participants must meet. Not everyone who applies will qualify, but those who do play a vital role in advancing healthcare and science.
What types of clinical research studies are available?

There are various types of clinical research studies, each designed to address specific health challenges, such as: Prevention Studies: Focused on discovering ways to prevent diseases in those who have never had them or to stop them from returning. Approaches may include medications, vaccines, vitamins, minerals, or lifestyle changes. Treatment Studies: Evaluate new therapies, drug combinations, or innovative approaches to treating diseases. Diagnostic Studies: Aim to develop improved tests or procedures for identifying specific diseases or conditions. Screening Studies: Explore the most effective methods for detecting diseases or health conditions early. Quality of Life (Supportive Care) Studies: Investigate ways to enhance comfort and overall well-being for individuals living with chronic illnesses. Typically, clinical trials compare a new product or treatment with an existing one to determine if it is equally effective or better at treating or preventing a disease. In blinded studies, participants are randomly assigned to receive either the investigational product or an approved therapy without knowing which they are receiving. Some studies also involve a placebo, a substance that resembles the test product but has no therapeutic effect. Comparing a treatment to a placebo is often the most efficient way to demonstrate its effectiveness. Before joining a trial, participants are fully informed about the study's details, including whether a placebo will be used, the potential risks, and the possible benefits of the investigational treatments.
What is a study protocol?

A clinical research study follows a structured research plan called a study protocol, created to address specific research questions and ensure participant safety. The protocol outlines key details, including: The purpose of the study Criteria for participant eligibility (inclusion and exclusion requirements) The number of participants required The schedule for tests, procedures, investigational treatments, and dosages The duration of the study The type of data to be collected about participants This protocol serves as a detailed guide for conducting the study and maintaining its scientific and ethical integrity.
Is my information kept confidential?

The clinical research team is committed to maintaining the strict confidentiality of your Personal Health Information (PHI). Your information will only be shared with your consent or when required by law. If you choose to provide your information through this website, and with your permission, it will be securely entered into our clinical research database for consideration in current and future study opportunities. You may request to have your information removed from the database at any time. Similarly, if you call and speak with one of our research specialists, your information will be securely added to the same database. Participation is entirely voluntary, and you can ask to have your information deleted at any time.

The Clinical Trial Participant Journey

Participating in a clinical trial is a voluntary decision, and you can choose to withdraw from the trial at any time if you change your mind. Before you enroll, you will go through a series of steps to ensure you meet the requirements of the trial and are informed about the risks and responsibilities of participating. This process will help you make an educated decision.

How clinical trials work - Health research tests new treatments through clinical trials. Learn what's involved.

1. Pre-Screening

First, you will learn about the trial. This may be done via online education, through a contact center, or at an appointment with the local research team. This education usually includes an understanding of you (and if appropriate, your match to the trial), the trial’s purpose, treatment information, potential benefits and risks, the length of your participation, and an overview of the trial’s activities.

2. Informed Consent

You will be provided with a document that details what you need to know as a trial participant so you can make an educated (informed) decision on whether you would like to take part in the trial. The clinical research coordinator will review the document with you and answer any questions you may have. You may want to bring a family member or friend to your appointment to help write down answers to your questions. If you decide to participate in the trial, you will sign the form, which provides your consent and acknowledges your understanding of the risks and your responsibilities. Even if you sign the consent form, you may withdraw from the trial at any time.

3. Screening

The informed consent form covers topics such as:

Purpose of the research
Who is eligible to participate
Expected length of time for participation
A description of the procedures (exams, tests, etc.) that will be part of the trial
A description of any expected risks
Possible discomforts (e.g., injections, frequency of blood tests, etc.)
Handling of data (e.g., confidentiality, record keeping, FDA inspections)
Who covers the cost if a clinical trial causes an injury
Participant rights (e.g., the right to stop participation at any time)
Who to contact if you have questions

During a participant screening visit, the research team will review your medical history and conduct any other procedures and tests (such as blood work, vitals, body measurements, biopsies, or scans) to make sure you meet all requirements to join the trial.

4. Enrollment and Participation

If you qualify, your participation can begin. The research team will provide detailed instructions on what you may need to do at home, how often you will need to visit the trial site, and what will be required at the visits (e.g., physical exams, questionnaires, tests, and procedures). Your overall health and safety are continually monitored for the duration of the trial. Taking part in a trial may require more doctor visits than usual, however many trials offer some reimbursement for your participation.

5. End of Trial Participation

Each trial has predefined trial completion criteria. When you complete your trial participation, you may meet with your regular healthcare provider, if different than your research team, to determine further care options. If you are a healthy volunteer, your commitment is over. Keep in mind that researchers can decide to end trials earlier than expected for a variety of reasons. You may also withdraw your consent to participate at any point during the trial.

Enhancing Healthcare For All

How to Participate in a Clinical Trial

To participate in our clinical trials, please register your details with us. This allows us to match you with a trial that fits your profile. Each study has specific eligibility criteria, including height, weight, and BMI requirements. Once registered in our database, we will review your information and notify you of suitable trials, including their purpose, eligibility requirements, and schedule.

The Benefits of Participation

Have you ever considered participating for a clinical trial, but felt unsure? There are numerous benefits to volunteering. We have highlighted a few reasons why you should participate in a clinical trial. These include the following.

Your participation matters and is a key part of medical innovation and advancement.

Learn more about your illness or condition. You may have the opportunity to receive diagnostic tests & exams at no cost.

Many clinical trial pay for your time and effort spent during the study. Compensation varies and is often contingent upon study length and requirements.

Many people hesitate to participate due to lack of insurance. Insurance is not required to participate. In addition, participating in a clinical trial may give you access to medication and care that previously felt unavailable.

Participating in clinical trial may give you access to cutting edge treatments and medical innovation at no cost and therefore your overall health may improve. In addition to studying the effectiveness of a treatment, researchers may also be investigating other aspects of care to improve the quality of life for people with chronic illness.

Phase II-IV clinical studies often require visits with a doctor who is an expert in the disease area being studied. Moreover, this study related care can help you learn valuable insights into your health with no long wait list or waiting rooms!

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Our Commitment

The importance of diverse participants

Individuals can respond differently to the same medication depending on factors such as age, gender, weight, race, ethnicity, and more. Clinical trials depend on the participation of volunteers to determine if medicines and vaccines are safe and effective across diverse communities.

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Valiance Clinical Research combines expertise, agility, and proactive strategies to optimize clinical development and help deliver impactful therapies to patients